Regeneration powered by nitrogen plasma
NeoGen harnesses controlled thermal energy from nitrogen plasma to stimulate a powerful physiological response within the skin, supporting regeneration, remodelling and long-lasting improvements in skin quality.
What is nitrogen plasma?
Nitrogen plasma is created by converting medical-grade nitrogen gas into an energised state called plasma. NeoGen delivers this thermal energy to the skin in precise, controlled pulses, rapidly heating the tissue and stimulating a natural healing response without creating an open wound.
How NeoGen harnesses nitrogen plasma
NeoGen converts nitrogen gas into pure nitrogen plasma, a controlled source of thermal energy that works throughout the skin’s architecture.
As each plasma pulse reaches the skin, it rapidly transfers heat into the tissue. This creates controlled zones of thermal damage and modification, triggering a significant physiological response.
By changing the energy delivered, practitioners can guide the depth of treatment and tailor the procedure to the patient and desired outcome.
*Energy range varies by NeoGen system.
What happens beneath the skin?
How does nitrogen plasma trigger skin regeneration?
When NeoGen delivers a pulse of nitrogen plasma, thermal energy rapidly heats the tissue. This creates two distinct areas: a Zone of Thermal Damage (ZTD) and a deeper Zone of Thermal Modification (ZTM).
Between these zones, a line of cleavage forms where a new epidermis develops. The outer layer of the skin remains in place during this process, acting as a natural dressing while the new epidermis forms beneath it.
What happens in the dermis?
The controlled thermal effect stimulates remodelling within the dermis. As part of the body’s response, new collagen and elastin are produced, progressively improving skin tightness, firmness and volume.
This regenerative process continues beyond the treatment itself, with studies showing continued neocollagenesis more than a year after treatment.
Why does the energy level matter?
Different energy settings create thermal effects at different depths.
At lower energies, treatment can support progressive results with less recovery time. Increasing the energy allows practitioners to target deeper remodelling within the dermis.
This gives trained practitioners the flexibility to tailor treatment according to the area being treated, the desired outcome and the patient’s expectations around recovery.
Nitrogen plasma FAQs
No. NeoGen uses nitrogen plasma as its source of thermal energy rather than laser light. The technology transfers controlled thermal energy directly into the tissue, creating a physiological response that stimulates regeneration and remodelling.
NeoGen does not create an open wound during treatment. The outer layer of skin remains intact, acting as a natural biological dressing while a new epidermis develops beneath it. This is one of the important differences between NeoGen and fully ablative technologies.
The depth of NeoGen’s thermal effect depends on the energy delivered. Practitioners can adjust the energy level to guide treatment depth, from lower-energy procedures through to higher-energy treatments targeting deeper remodelling within the dermis.
The controlled thermal response triggers remodelling within the dermis and stimulates the production of collagen and elastin. These structural changes contribute to progressive improvements in skin tightness, firmness and volume.
No. NeoGen works across the skin’s architecture, with thermal effects extending from the epidermis into the dermis. Higher energy settings allow practitioners to target deeper dermal remodelling.
NeoGen converts nitrogen gas into plasma to create a controlled source of thermal energy. This energy can then be delivered in precise pulses to produce a predictable thermal effect within the tissue.
Yes. Depending on the NeoGen system, practitioners can select different energy levels to tailor the treatment. NeoGen EVO provides an energy range from 0.5J to 4.0J.
Lower-energy treatments are designed to deliver progressive, cumulative results with less recovery time. Higher energy levels create a deeper thermal effect and can be used when greater dermal remodelling is required.
The appropriate energy level and treatment protocol depend on the treatment objective and should be determined by a trained practitioner.
The biological response initiated by treatment continues as the skin remodels. NeoGen materials report studies showing continued neocollagenesis more than one year after treatment, supporting the technology’s focus on progressive, regenerative results.
NeoGen is used for aesthetic and dermatological treatments across the face, body and periorbital area. Specific medical indications and permitted uses depend on the NeoGen system and the applicable regulatory certification in each market.